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19. January 2021 16:11
by Admin

Hydroxychloroquine: The unproven 'corona drug'

19. January 2021 16:11 by Admin | 0 Comments

Hydroxychloroquine: The unproven 'corona drug' Trump is threatening India for

  • Coronavirus pandemic

US President Donald Trump has said the US could "retaliate" if India does not release stocks of a drug he has called a "game-changer" in the fight against Covid-19.

Mr Trump had called India's Prime Minister Narendra Modi on Sunday, a day after the country banned the export of hydroxychloroquine, which it manufactures in large quantities.

Local media said the government was "considering" Mr Trump's request and a decision is expected on Tuesday.

The US President's comments, made at the White House press briefing on Monday, haven't gone down well with many in India, with critics pointing out that there was no need for him to be so abrasive when Mr Modi has already agreed to help.

The two leaders are on friendly terms and Mr Trump had made a high-profile trip to India recently.

But is India really in a position to help the US? And does hydroxychloroquine even work against the coronavirus?

What is hydroxychloroquine?

Hydroxychloroquine is very similar to Chloroquine, one of the oldest and best-known anti-malarial drugs.

But the drug - which can also treat auto-immune diseases like rheumatoid arthritis and lupus - has also attracted attention over the past few decades as a potential antiviral agent.

President Trump said that the US Food and Drug Administration (FDA) had approved it for treating coronavirus, something the organization has denied. Mr Trump later said that it had been approved for "compassionate use" - which means a doctor can give a drug that is yet to be cleared by the government to a patient in a life-threatening condition.

Doctors are able to prescribe chloroquine in these circumstances as it's a registered drug.

So, can India really help President Trump?

Hydroxychloroquine could be bought over the counter and is fairly inexpensive. However, its purchase and use has been severely restricted ever since it was named as a possible treatment for Covid-19.

On Saturday, India banned the export of the drug "without any exception". The order came even as the number of positive cases of Covid-19 spiked in the country. India has now recorded 3,666 active cases of the virus with more than 100 deaths, according to the latest data released by the ministry of health.

But now it seems the government could be reconsidering this stance, possibly following Mr Trump's call to Mr Modi. Local media quoted government sources as saying that a decision on this could be taken as early as Tuesday after considering what domestic requirements could look like in the near future.

The two leaders have a warm personal relationship

But does India - one of the world's largest manufacturers of the drug - have the capacity to actually supply other countries as well?

Yes, according to Ashok Kumar Madan, of the Indian Drug Manufacturer's association.

"India definitely has capacity to cater to both global and local markets. Of course, domestic considerations must come first, but we have the capacity," he told the BBC.

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Mr Madan also denied reports that China had severely limited the export of the active pharmaceutical ingredient (API) that is used to manufacture hydroxychloroquine. He acknowledged that 70% of all the APIs needed by India to manufacture drugs come from China, but said that supplies from China had steadily continued "by both sea and air".

But does it work?

Many virologists and infectious disease experts have cautioned that the excitement over hydroxychloroquine is premature.

"Chloroquine seems to block the coronavirus in lab studies. There's some anecdotal evidence from doctors saying it has appeared to help," James Gallagher, BBC health correspondent, explained.

But crucially there have been no complete clinical trials which are important to show how the drug behaves in actual patients, although they are under way in China, the US, UK and Spain.

Even so, some are sceptical about how successful they will prove to be.

"If it truly has a dramatic effect on the clinical course of Covid-19 we would already have evidence for that. We don't, which tells us that hydroxychloroquine, if it even works at all, will likely be shown to have modest effects at best," Dr Joyeeta Basu, a senior consultant physician, told the BBC.

American scientists have begun a trial to see if chloroquine will help treat coronavirus

Raman R Gangakhedkar, a senior scientist with the Indian Council of Medical Research, said the policy at the moment is that the drug is not to be used by everyone.

"It is being given to doctors and contacts of lab confirmed cases. When their data will be complied only then a call can be taken whether it should be recommended to everyone," he told reporters last week.

Despite the fact trials are yet to conclude, people have begun to self-medicate - with sometimes disastrous consequences.

There have been multiple reports in Nigeria of people being poisoned from overdoses after people were reportedly inspired by Mr Trump's enthusiastic endorsement of the drug.

An article in the Lancet medical journal also warns hydroxychloroquine can have dangerous side-effects if the dose is not carefully controlled.

This lack of certainty has prompted social media sites like Facebook and Twitter to delete posts that tout it as a cure - even when they are made by world leaders.

19. January 2021 16:02
by Admin

French professor faces disciplinary case over hydroxychloroquine claims

19. January 2021 16:02 by Admin | 0 Comments


French professor faces disciplinary case over hydroxychloroquine claims | World news | The Guardian

French professor faces disciplinary case over hydroxychloroquine claims


Didier Raoult stands accused of touting drug as a coronavirus treatment without evidence

Didier Raoult’s promotion of the drug as a Covid treatment was taken up by some populist world leaders. Photograph: Christophe Simon/AFP/Getty Images

A French professor who touts the anti-malaria drug hydroxychloroquine as a coronavirus treatment – without evidence, scientists say – will appear before a disciplinary panel charged with ethics breaches, an order of doctors has said.

Marseille-based Didier Raoult stands accused by his peers of spreading false information about the benefits of the drug. His promotion of hydroxychloroquine was taken up by the US and Brazilian presidents, Donald Trump and Jair Bolsonaro, who trumpeted its unproven benefits in a way critics say put people’s lives at risk.

No clinical trials have yet found in favour of using hydroxychloroquine against Covid-19, and critics say that due to potential serious side-effects, treating coronavirus patients with it is worse than no treatment at all.

In June, the British-led Recovery trial team said hydroxychloroquine did nothing to reduce coronavirus mortality.

A group representing 500 specialists of France’s Infectious Diseases Society (SPILF) filed a complaint with the national order of doctors of the Bouche-du-Rhône department, which includes Marseille, in July. They accused Raoult of breaking nine rules of the doctors’ code of ethics. Other doctors and patients have also lodged complaints.

On Thursday, the order confirmed it had given the go-ahead for a disciplinary hearing after reviewing the complaints against Raoult. The hearing will probably take place next year.

Raoult’s lawyer, Fabrice Di Vizio, confirmed they had received notice of the decision, but said his client would be cleared. If found guilty, Raoult could be fined, merely warned, or barred from practising.

Raoult, who heads the infectious diseases department of La Timone hospital in Marseille, said in March that his study of 80 patients showed “favourable” outcomes in four out of five treated with hydroxychloroquine. But his peers say there is no scientific evidence to back up the claim.

The French president, Emmanuel Macron, visited the scientist on 9 April, at the height of the pandemic, when people in France were observing strict stay-at-home rules.


22. December 2020 15:11
by Admin

Is it all just a joke?

22. December 2020 15:11 by Admin | 0 Comments

Covidien - manufacturers of ventilators since 2007...

In 2007, Covidien was formed when Tyco International spun off its health care business. Since that time, Covidien has made a number of acquisitions including VNUS Medical Technologies, Aspect Medical Systems, Somanetics, ev3, BÂRRX, Newport Medical Instruments, superDimension, Oridion Systems and Given Imaging. Offshoring and focus on low cost countries (LCC) resulted in several plant closures in the USA particularly a few in upper New York state and Norwood, Massachusetts.

In 2011, José E. Almeida became the Chairman, CEO, and President.

In 2012, Covidien acquired Newport Medical Instruments, a small ventilator manufacturer supplier. Newport Medical Instruments had been contracted in 2006 by the U.S. Department of Health and Human Services' Biomedical Advanced Research and Development Authority to design a cheap, portable ventilator. At the time, Newport Medical Instruments had 3 working prototypes produced, and was on schedule to file for market approval late 2013. Covidien then effectively halted the project, subsequently exiting the contract, as it was not profitable enough. Government officials and other medical equipment suppliers suspect the Newport acquisition was largely done to prevent a cheaper product from undermining Covidien's existing ventilator business. This contributed to the shortage of ventilators during the COVID-19 pandemic.

22. November 2020 12:55
by Admin

COVID 19 The Big Picture - Andrew Johnson

22. November 2020 12:55 by Admin | 0 Comments

COVID 19 The Big Picture - Andrew Johnson


What are the facts concerning COVID 19 and SARS-COV2 and what is the likely agenda of the perpetrators if the truth has not been told.

The COVID-19 test is unreliable and has no bearing on whether you have or will ever have any type of disease. The COVID-19 strain has never been isolated by anyone and so no test can prove whether it has ever killed anyone as there is no unpolluted sample. They have redefined the word 'case' to mean positively tested for, but the test cannot be trusted, so the number of cases cannot be either. Whatever this nasty flu that some people have had is, it is not confirmed as anything medically defined as COVID-19 and so the figures have no basis in fact. The inventor of the test has made it clear that the test cannot be used to track disease or infection. Your freedom is at stake here, not your health. It is becoming illegal to go and meet your friends in the Western World, this is not the time to worry about politicians or their statistics.



From Wikipedia: 

A French national hero at age 55, in 1878 Pasteur discreetly told his family never to reveal his laboratory notebooks to anyone. His family obeyed, and all his documents were held and inherited in secrecy. Finally, in 1964 Pasteur's grandson and last surviving male descendant, Pasteur Vallery-Radot, donated the papers to the French national library (Bibliothèque nationale de France). Yet the papers were restricted for historical studies until the death of Vallery-Radot in 1971. The documents were given a catalogue number only in 1985.

In 1995, the centennial of the death of Louis Pasteur, a historian of science Gerald L. Geison published an analysis of Pasteur's private notebooks in his The Private Science of Louis Pasteur, and declared that Pasteur had given several misleading accounts and played deceptions in his most important discoveries.


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